Circulatory system diseases were the leading cause of premature death in OECD countries in 2021, accounting for over one-third of all premature deaths. Cancer was the second most common cause of premature deaths, accounting for 23% of all premature deaths. Respiratory system diseases, diabetes, other endocrine diseases, and all other causes accounted for the remaining share of premature deaths. The WHO Mortality Database also states that some cancers that are preventable through public health measures are the main causes of preventable mortality.